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ProAir® HFA Dosage
and Administration


  • For oral inhalation only1
  • Acute Bronchospasm
    • 2 inhalations repeated every 4 to 6 hours1
    • More frequent administration or a larger number of inhalations is not recommended
    • Some patients may need only 1 inhalation every 4 hours
  • Exercise-induced bronchospasm (EIB):
    • 2 inhalations 15 to 30 minutes before exercise1

Using and cleaning the ProAir® HFA inhaler


Before first use and after more than 14 days of non-use, ProAir HFA must be primed by
releasing 3 sprays into the air, shaking well before each spray.1


Dose Counter

With a built-in dose counter,1 The Red Inhaler is…
a rescue inhaler that lets patients know they have medicine when they need it most.

full counter


Patients know how many doses are left

22-20 counter


When dose counter numbers turn red, patients are reminded it’s time to refill
their prescription

full counter


When the window background turns red, it’s time to replace the inhaler


ProAir HFA (albuterol sulfate) Inhalation Aerosol is indicated in patients ≥4 years of age for the treatment or prevention of bronchospasm with reversible obstructive airway disease and in patients ≥4 years of age for the prevention of exercise-induced bronchospasm.

Important Safety Information

  • Contraindications: ProAir HFA is contraindicated in patients with hypersensitivity to albuterol
  • Paradoxical Bronchospasm: ProAir HFA can produce paradoxical bronchospasm that may be life-threatening. Discontinue ProAir HFA and institute alternative therapy if paradoxical bronchospasm occurs
  • Deterioration of Asthma: Need for more doses of ProAir HFA than usual may be a marker of acute or chronic deterioration of asthma and requires reevaluation of treatment, such as possible need for anti-inflammatory treatment, e.g., corticosteroids
  • Use of Anti-Inflammatory Agents: ProAir HFA alone may not be adequate to control asthma in many patients. Early consideration should be given to adding anti-inflammatory agents, e.g., corticosteroids
  • Cardiovascular Effects: ProAir HFA, like other beta-adrenergic agonists, can produce clinically significant cardiovascular effects in some patients, as measured by heart rate, blood pressure, and/or symptoms. If such effects occur, the drug may need to be discontinued. ProAir HFA, like all sympathomimetic amines, should be used with caution in patients with cardiovascular disorders, especially coronary insufficiency, cardiac arrhythmias, and hypertension
  • Do Not Exceed Recommended Dose: Fatalities have been reported in association with excessive use of inhaled sympathomimetic drugs in patients with asthma
  • Immediate Hypersensitivity Reactions may occur after administration of albuterol sulfate, as demonstrated by rare cases of urticaria, angioedema, rash, bronchospasm, anaphylaxis, and oropharyngeal edema
  • Coexisting Conditions: ProAir HFA, like all sympathomimetic amines, should be used with caution in patients with convulsive disorders, hyperthyroidism, or diabetes mellitus; and in patients who are unusually responsive to sympathomimetic amines.
  • Hypokalemia: As with other beta-agonists, ProAir HFA may produce significant hypokalemia in some patients. The decrease is usually transient, not requiring supplementation
  • Most common adverse reactions (≥3.0% and >placebo): are headache, tachycardia, pain, dizziness, pharyngitis, and rhinitis
  • Drug Interactions: Other short-acting sympathomimetic bronchodilators should not be used concomitantly with ProAir HFA
    • Beta-Blockers: Beta-adrenergic-receptor blocking agents not only block the pulmonary effect of beta-agonists, such as ProAir HFA, but may produce severe bronchospasm in asthmatic patients. Therefore, patients with asthma should not normally be treated with beta-blockers
    • Diuretics: Caution is advised in the coadministration of beta-agonists with non-potassium sparing diuretics (such as loop or thiazide diuretics). Consider monitoring potassium levels
    • Digoxin: Carefully evaluate the serum digoxin levels in patients who are currently receiving digoxin and ProAir HFA
    • Monoamine Oxidase Inhibitors or Tricyclic Antidepressants: ProAir HFA should be administered with extreme caution to patients being treated with these agents, or within 2 weeks of discontinuation of these agents, because the action of albuterol on the cardiovascular system may be potentiated. Consider alternative therapy

  • Please read the full Prescribing Information.


1.ProAir HFA Prescribing Information. Parsippany, NJ: Teva Respiratory, LLC.